110 Grey’s Anatomy Quotes on Life, Friendship, and More

This show is something that most readers would consider a ‘classic’ and a ‘must-have’ reference for life, so we’ve rounded up the best Grey’s Anatomy quotes that’ll give you an emotional roller coaster ride—bringing all the emotions of the show and as well as some valuable life lessons you can refer to when you’re feeling down.

Grey’s Anatomy has been on air and on our screens since 2005, and is now considered to be the longest-running, scripted, prime-time show on ABC.

It’s been a crazy ride for both the characters and the audience, but because of it’s intense storylines and conflicts, and of course, the amazing words of wisdom from our beloved characters, everyone still looks back and watches the show over a decade later.

Check out our list below.

And be sure to read these Supernatural quotes and Criminal Minds quotes.

Best Grey’s Anatomy Quotes

Grey's Anatomy Quote - Don't let what he wants eclipse what you need. He's very dreamy, but he's not the sun.

1. “Don’t let what he wants eclipse what you need. He’s very dreamy, but he’s not the sun. You are.” – Christina Yang

2. “Sometimes, it’s good to be scared. It means you still have something to lose.” – Richard Webber

3. “I am not an ugly duckling. I’m a swan.” – April Kepner

4. “Uprooting my entire life is not an inconvenience!” – April Kepner

Grey's Anatomy Quote - Mistakes are painful, but they're the only way to find out who we really are.

5. “It turns out sometimes you have to do the wrong thing. Sometimes, you have to make a big mistake to figure out how to make things right. Mistakes are painful, but they’re the only way to find out who we really are.” – Denny Duquette

6. “You were like coming up for fresh air. It’s like I was drowning and you saved me. That’s all I know.” – Derek Shepherd

7. “‘Cause you never think that the last time is the last time. You think there will be more. You think you have forever, but you don’t.” – Meredith Grey

Related: Meredith Grey Quotes

8. “Oh screw beautiful! I’m brilliant! If you want to appease me, compliment my brain.” – Christina Yang

9. “In the beginning, everyone is there, but then they forget.” – Amelia Shepherd

Grey's Anatomy Quote - But Derek, I love you, in a really, really big 'pretend to like your taste in music, let you eat the last piece of cheesecake, hold a radio over my head outside your window.' unfortunate way.

10. “Okay, here it is, your choice—it’s simple, her or me, and I’m sure she is really great. But Derek, I love you, in a really, really big ‘pretend to like your taste in music, let you eat the last piece of cheesecake, hold a radio over my head outside your window,’ unfortunate way that makes me hate you, love you.” – Meredith Grey

11. “I’ve had to give up things but what I’ve learned is that I don’t need much. I don’t need much to be happy.” – Arizona Robbins

12. “Being aware of your crap and actually overcoming your crap are two very different things” – Cristina Yang

Related: Cristina Yang Quotes

13. “You didn’t love her! You just didn’t want to be alone. Or maybe, maybe she was good for your ego. Or, or maybe she made you feel better about your miserable life, but you didn’t love her, because you don’t destroy the person that you love!” – Callie Torres

14. “I love you. I do. I just, I love you. And I have been trying not to say it. I have been trying so hard to just mash it down and ignore it and not say it and Jackson is a great guy. But it was never gonna work out, because I love you.” – Lexie Grey

Grey's Anatomy Quote - Knowing is better than wondering. Waking is better than sleeping.

15. “Knowing is better than wondering. Waking is better than sleeping, and even the biggest failure, even the worst, beats the hell out of never trying.” – Meredith Grey

16. “You have to go back to the beginning to understand the end.” – Teddy Altman

17. “If you want crappy things to stop happening to you, stop accepting crap and demand something more.” – Cristina Yang

18. “I need the day off. For drinking.” – Addison Montgomery

19. “Yeah we’re friends. I mean, right now I’d probably say you’re one of my best friends.” – George O’Malley

Related: One Tree Hill Quotes, This Is Us Quotes

Famous Grey’s Anatomy Quotes

Grey's Anatomy Quote - And I want you with me. I love you and I think you love me too.

20. “I love everything about you. Even the things I don’t like, I love. And I want you with me. I love you and I think you love me too. Do you?” – Jackson Avery

21. “Each of you comes here today hopeful—wanting in on the game. A month ago, you were in med school being taught by doctors. Today, you are the doctors. The seven years you spend here as a surgical residents will be the best and worst of your life. You will be pushed to the breaking point. Look around you. Say hello to your competition. Eight of you will switch to an easier specialty. Five of you will crack under the pressure and two of you will be asked to leave. This is your starting line. This is your arena.” – Richard Webber

Best Quotes On Fake Friends
Best Quotes On Fake Friends

22. “I am a woman. Hear me roar.” – Miranda Bailey

23. “How well will you play? That’s up to you.” – Richard Webber

24. “It’s a beautiful day to save lives.” – Derek Shepherd

Grey's Anatomy Quote - Just because people do horrible things, it doesn't always mean they're horrible people.

25. “Just because people do horrible things, it doesn’t always mean they’re horrible people.” – Izzie Stevens

26. “So pick me, choose me, love me.” – Meredith Grey

27. “You can have the worst crap in the world happen to you and you can get over it. All you gotta do is survive.” – Alex Karev

28. “Walk tall. All you can do is be brave enough to get out there. You fought. You loved. You Lost. Walk tall.” – Mark Sloan

29. “I am so in love with you. You’re in me. It’s like you’re a disease. It’s like I am infected by Mark Sloan and I just can’t think about anything or anybody and I can’t sleep. I can’t breathe. I can’t eat. And I love you. I love you all the time. Every minute of every day. I love you. God, that feels good to just say that. I feel so much better. I love you.” – Lexie Grey

Also read: Friday Night Lights Quotes

Grey’s Anatomy Quotes on Hard Work and Perseverance

Grey's Anatomy Quote - If you aren't willing to keep looking for light in the darkest of places without stopping, even when it seems impossible, you will never succeed.

30. “If you aren’t willing to keep looking for light in the darkest of places without stopping, even when it seems impossible, you will never succeed.” – Amelia Shepherd

31. “Grief comes in it’s own time for everyone in it’s own way. So the best we can do—the best anyone can do—is try for honesty.” – Meredith Grey

32. “The really crappy thing—the very worst part of grief—is that you can’t control it. The best we can do is try to let ourselves feel it when it comes and let it go when we can.” – Meredith Grey

33. “Let’s play a game of whose life sucks the most. I’ll win. I always win.” – Meredith Grey

34. “Don’t let fear keep you quiet. You have a voice so use it. Speak up. Raise your hands. Shout your answers. Make yourself heard.” – Meredith Grey

Grey's Anatomy Quote - Whatever it takes, just find your voice, and when you do, fill the damn silence.

35. “Whatever it takes, just find your voice, and when you do, fill the damn silence.” – Meredith Grey

36. “We’re adults. When did that happen? How do we make it stop?” – Meredith Grey

37. “Hope. It’s recurrent, it keeps creeping back in no matter how many times it gets ripped apart and every time the hope goes it takes chunks of you with it.” – Nicole Herman

38. “The thing we gotta try to remember is that it can turn on a dime. That’s how you stay alive when it hurts so much you can’t breathe. That’s how you survive. By remembering that one day somehow, impossibly, it won’t feel this way. It won’t hurt this much.” – Meredith Grey

39. “You can’t be an ass to me all day and then expect me to give you respect.” – Lexie Grey

Grey's Anatomy Quote - Please don't give up on me. Promise. Promise me you won't.

40. “Please don’t give up on me. Promise. Promise me you won’t.” – Arizona Robbins

41. “Bad things happen, but you have to move past it. Leave it behind. The sooner, the better. Or it’ll eat away at you and stop you from moving forward.” – Miranda Bailey

42. “Why does it feel so good to get rid of things? To unload? To let go? Maybe because when we see how little we actually need to survive, it makes us realize how powerful we actually are. To strip down to only what we need. To hang on to only what we can’t do without. Not just to survive, but to thrive.” – Meredith Grey

43. “It’ll hurt every time you think of her. But over time, it will hurt less and less. And eventually, you’ll remember her and it will only hurt a little.” – Cristina Yang

44. “Grief may be a thing we all have in common, but it looks different on everyone. It isn’t just death we have to grieve. It’s life, it’s loss, it’s change. And when we wonder why it has to suck so much sometimes, it has to hurt so bad.” – Meredith Grey

Grey's Anatomy Quote - Make a plan. Set a goal. Work toward it, but every now and then look around.

45. “Make a plan. Set a goal. Work toward it, but every now and then look around. Drink it in, ’cause this is it. It might all be gone tomorrow.” – Meredith Grey

46. “So you fight, until you can’t fight anymore.” – Amelia Shepherd

47. “You’re allowed to want what you want even if it’s not what he wants.” – Richard Webber

48. “Helm, you can either live here or talk, but you can’t do both.” – Jo Wilson

49. “I think you have to stop asking if you can do it, Jo, and realize that you already are.” – Link

Grey’s Anatomy Quotes That Are All About Love

Grey's Anatomy Quote - I'm just gonna feel bad that I made it so you can never love again.

50. “I’m just gonna feel bad that I made it so you can never love again.” – Jo Wilson

51. “If you love someone, you tell them. Even if you’re scared that it’s not the right thing. Even if you’re scared that it’ll cause problems. Even if you’re scared that it will burn your life to the ground, you say it, and you say it out loud and you go from there.” – Mark Sloan

52. “Stop looking at me like that. Like you’ve seen me naked.” – Meredith Grey

53. “Deal with your jealousy. Deal with your shortcomings. Don’t put your crap on me.” – Stephanie Edwards

54. “I know I’m not a lot of things that you’ve gone for in the past. I know, but I would never leave you. I would never hurt you. And I will never stop loving you.” – George O’Malley

Grey's Anatomy Quote - More tequila. More love. More anything. More is better.

55. “More tequila. More love. More anything. More is better.” – Meredith Grey

56. “For a kiss to be really good, you want it to mean something. You want it to be with someone you can’t get out of your head, so that when your lips finally touch you feel it everywhere. A kiss so hot and so deep you never want to come up for air. You can’t cheat your first kiss. Trust me, you don’t want to. Cause when you find that right person for a first kiss, it’s everything.” – Alex Karev

57. “Shut up. Dance it out.” – Cristina Yang

58. “We may only be together five minutes every two months, but when we do, we will savor every second. We know how valuable those five minutes are.” – Ben Warren

59. “The problem is we are human. We want more than to just survive. We want to love.” – Lexie Grey

Grey's Anatomy Quote - A weight lifts, the sun shines a little brighter, and for a brief moment, we find a little peace.

60. “It’s funny, isn’t it? A weight lifts, the sun shines a little brighter, and for a brief moment, we find a little peace.” – Meredith Grey

61. “I’m up there waiting for you to come down the aisle and I know you don’t want to come. If I loved you, I wouldn’t be up there waiting for you. I would be letting you go.” – Preston Burke

62. “You think you broke me, little grey? You’re the one who put me back together.” – Mark Sloan

63. “I want so much for you—for both of us. So much more than this. More than being stuck with someone who feels stuck. I want you to feel free.” – Callie Torres

64. “Whoever said, ‘What you don’t know can’t hurt you,’ was a complete and total moron. Sometimes not knowing is the worst thing in the world.” – Meredith Grey

Grey's Anatomy Quote - Every kiss before the right kiss doesn't count anyway.

65. “Every kiss before the right kiss doesn’t count anyway.” – Derek Shepherd

66. “Promise that you’ll love me, even when you hate me.” – Meredith Grey

67. “The problem is, fairytales don’t come true. It’s the nightmares that always seem to become the reality.” – Meredith Grey

68. “How are you fine? How are you just completely fine? I am ruined, okay? I am dead, I am wrecked.” – Cristina Yang

69. “Some lies aren’t lies. They’re love.” – Meredith Grey

Grey’s Anatomy Quotes on Life and Aspirations

Grey's Anatomy Quote - The future is the home of our deepest fears and our wildest hopes.

70. “The future is the home of our deepest fears and our wildest hopes.” – Owen Hunt

71. “I take things personally. I get emotional.” – Lexie Grey

72. “Pretty good is not good enough. I want to be great.” – Cristina Yang

73. “Sometimes, you have to be a shark.” – Lucy Fields

74. “You are in a spaceship. You’re going to the moon. Enjoy the ride.” – Alex Karev

Grey's Anatomy Quote - My good relationships started out as friends and then became more and then you know, died - screaming.

75. “My good relationships started out as friends and then became more and then you know, died—screaming.” – Maggie Pierce

76. “Maybe it’s this expectation of wanting to be happy that just keeps us from ever getting there. Maybe the more we try to bring ourselves to state’s of bliss, the more confused we get—to the point where we don’t recognize ourselves. Instead, we just keep smiling—trying to be the happy people we wish we were. Until it eventually hits us, it’s been there all along. Not in our dreams or our hopes, but in the known, the comfortable, the familiar.” – Meredith Grey

77. “There comes a point when you have to suck it up. and stop whining, and start living.” – Callie Torres

78. “Yes, horrible things do happen. Happiness, in the face of all of that, that’s not the goal. Feeling horrible, and knowing that you’re not gonna die from those feelings, that’s the point.” – Katherine Wyatt

79. “The body is a slave to its impulses. But the thing that makes us human is what we can control. After the storm, after the rush, after the heat of the moment has passed, we can cool off and clean up the mess we made. We can try to let go of what was.” – Meredith Grey

Grey's Anatomy Quote - Why don't we just pack it in and go home?

80. “Why do we even try when the barriers are so high and the odds are so low? Why don’t we just pack it in and go home?” – Amelia Shepherd

81. “Ask most people what they want out of life and the answer is simple—to be happy.” – Meredith Grey

82. “Picture the life you dreamed of living. Are you living the life you envisioned for yourself? Are you who you wanted to be when you grew up?” – Meredith Grey

83. “Don’t analyze everything. Just do it.” – Alex Karev

84. “That’s where love exists—in delusional fantasies.” – Meredith Grey

Grey's Anatomy Quote - It's you and me - the plastic posse.

85. “It’s you and me—the plastic posse. Kicking ass and taking names.” – Mark Sloan

86. “I’m a superstar—superstar with a scalpel.” – Callie Torres

87. “We don’t get unlimited chances to have the things that we want, and this I know. Nothing is worse than missing an opportunity that could have changed your life.” – Addison Montgomery

88. “Friends are the family we choose.” – Meredith Grey

89. “Don’t ever date a man who can’t handle your power.” – Meredith Grey

Inspirational and Humorous Grey’s Anatomy Quotes

Grey's Anatomy Quote - Not everyone has to be happy all the time. That isn't mental health. That's crap.

90. “Not everyone has to be happy all the time. That isn’t mental health. That’s crap.” – Meredith Grey

91. “There’s a land called passive agressiva, and you’re their queen.” – Derek Shepherd

92. “Let’s just make-out on the couch.” – Nathan Riggs

93. “Maybe we like the pain. Maybe we’re wired that way. Because without it, I don’t know; maybe we just wouldn’t feel real. What’s that saying? Why do I keep hitting myself with a hammer? Because it feels so good when I stop.” – Meredith Grey

94. “Every intern wants to perform their first surgery. That’s not your job. Do you know what your job is? To make your resident happy. Do I look happy? No! Why? Because my interns are whiney. You know what will make me look happy? Having the code team staffed, having the trauma pages answered, having the weekend labs delivered and having someone down in the pit doing the sutures. No one holds a scalpel until I’m so happy I’m Mary Freaking Poppins.” – Miranda Bailey

Grey's Anatomy Quote - Don't look at me like that. Like I'm damaged goods.

95. “Don’t look at me like that. Like I’m damaged goods. I’m still me. I’m still here.” – Adele Webber

96. “I can do hot in my sleep. I look hot in scrubs. I am a hot person.” – Cristina Yang

97. “You grew up. It’s a shame, an awful thing to grow up. The carousel never stops turning. You can never get off.” – Ellis Grey

98. “Some days, the whole world seems upside down. And then somehow, and probably, when you least expect it, the world gets right again.” – Meredith Grey

99. “Knowing is better than wondering, waking is better than sleeping, and even the biggest failure, even the worst, beats the hell out of never trying.” – Meredith Grey

Grey's Anatomy Quote - This is the way the world changes. Good people, raising babies right.

100. “This is the way the world changes. Good people, raising babies right.” – Catherine Avery

101. “You know, he’s acting like I committed a crime. Like my apartment is full of stolen goods. He’s acting like I kept my apartment to hide stolen goods, so I could do illegal organ transplants for money.” – Cristina Yang

102. “There’s a club—the Dead Dads Club. And you can’t be in it until you’re in it. You can try to understand, you can sympathize, but until you feel that loss,my dad died when I was nine. George, I’m really sorry you had to join the club.” – Cristina Yang

103. “I’m going to die because these people aren’t properly trained.” – Derek Shepherd

104. “I believe if you were dead, the world would be a better place.” – George O’Malley

Grey's Anatomy Quote -  It's the unexpected that changes our lives forever.

105. “The expected is what keeps us steady. It’s the unexpected that changes our lives forever.” – Meredith Grey

106. “I didn’t like teenage girls when I was a teenage girl.” – Cristina Yang

107. “Do not alarm the makers of the tiny humans. They will eat you.” – Arizona Robbins

108. “I’m a better woman than you.” – Mark Sloan

109. “Breakthroughs don’t happen because of the medicine. Real breakthroughs happen because someone is scared to death to stop trying.” – Derek Shepherd

Grey's Anatomy Quote - Human life is made up of choices. Live or die. That's the important choice. And it's not always in our hands.

110. “Yes or no. In or out. Up or down. Live or die. Hero or coward. Fight or give in. I’ll say it again to make sure you hear me. Human life is made up of choices. Live or die. That’s the important choice. And it’s not always in our hands.” – Derek Shepherd

Did These Grey’s Anatomy Quotes Give You the Strength to Power on Through Life’s Challenges?

With more than a decade of air time, we’ve certainly watched the characters of Grey’s Anatomy grow up in front of our own eyes. We’ve seen all their ups and their downs, and all their failures and victories.

But above all, we’ve seen how they learn from each and everything they face—whether it’s positive or not. And maybe, out of all the life lessons in the show, what’s really important is that it taught us to move on from our mistakes.

Because after all, while it’s important to learn our lessons, it’s equally important to not wallow in our mistakes forever and instead take that next step forward.

Did you also watch Grey’s Anatomy when you were growing up? Which quotes are your favorites? We hope you can share your thoughts down below!